Frailty is a common clinical condition in older adults,
which confer high risk for falls, disability, hospitalization and mor-
tality [1,2]. This systematic review, developed within the context of
and funded under the European Union
Health Programme (2014
2020), aimed to summarize the best avail-
able evidence in relation to the effectiveness of the interventions in
preventing progression of frailty in older adults.
The review process was based on Joanna Briggs Institute
procedures . Databases were searched for all published and unpub-
lished studies from January 2001 to November 2015, with participants
aged 65 and over, explicitly identified as pre-frail or frail and receiving
health care and support services in any type of setting. The inter-
ventions of interest were those focusing on the prevention of frailty
progress, as compared to usual care, alternative therapeutic interven-
tions or no intervention. Both clinical/medical and economic compo-
nents of the interventions were addressed.
A total of 2,507 records were screened by title and abstracts
and 2,121 irrelevant records were excluded. Presently, 386 full-text
articles are assessed for inclusion criteria and methodological quality.
The extraction of data from the eligible articles will consider changes
in frailty (primary outcome), changes in different functional domains
and in indicators of adverse outcomes, and economic data associated
with implementing of the interventions (secondary outcomes).
It is expected that the results of this systematic
review will have positive impact on care for older adults, minimizing
the risk of adverse consequences and ameliorating the consequences
on independence or healthy and engaged lifestyles.
1. Clegg A, Young J, Iliffe S,
Frailty in elderly people.
2. Fried LP, Ferrucci L, Darer J,
Untangling the concepts of
disability, frailty, and comorbidity: implications for improved
targeting and care.
J Gerontol A Biol Sci Med Sci
3. The Joanna Briggs Institute.
Joanna Briggs Institute Reviewers
. Adelaide: Author; 2014.
Handgrip strength and cognitive function in the frail elderly
, P. Gareri
, C. Ruberto
, M. Stagliano
, M. Rocca
Health Authority Catanzaro,
Health Home Chiaravalle, Provincial Health
Provincial Health Authority Catanzaro
Handgrip is a reliable single marker of frailty in older
people and can predict falls, disability, hospital admissions, and
mortality. In primary care units Frailty Ambulatory is dedicated to
elderly people and is an example of health innovation. The aim of this
study was to investigate the association between handgrip test (HT)
and cognitive function in the frail elderly.
Frailty Ambulatories have to facilitate the
complex elderly patients
needs through geriatricians and out-of-
hospital network services. The aim of the present study was to analyze
data from 300 consecutive patients visited in our ambulatories.
The starting point is caring patients and their needs. The first step
is represented by over-65 year-old patients
selection according to
prefrailty and frailty Fried
s criteria. We performed multidimensional
assessment and HT in all the patients.
Of 300 patients, 118 (39,3%) were men, mean age 82,79 ± 6,65
years old; BMI was 22,17 ± 2,15 kg/m
. After performing multidimen-
sional assessment we found the following scores: MMSE 11,05 ± 2,44;
ADL 0,95 ± 2,06; IADL 0,04 ± 0,188; CIRS 4,95 ± 1,72. The HT was
28,03 + 8,25 Kg. After bivariate analysis, we found a significant
relationship among MMSE and HT, CIRS and number of drugs used.
After multivariate analysis the relationship was also present with
HT (beta 0,507; p = 0,000) and CIRS (beta
0,345; p = 0,001).
Experimental activity in Frailty Ambulatories could
offer a tool able to recognize conditions of prefrailty/frailty. Frailty,
assessed through HT and cognitive functions are significanty related in
the frail elderly.
Frailty is associated with socioeconomic and lifestyle factors in
community-dwelling older subjects
, S. Poli
, M. Puntoni
, C. Musacchio
, M. Pomata
, D. Torriglia
, B. Molinari
, V. Pandolfini
, C. Torrigiani
, A. Pilotto
Department of Geriatric Care, OrthoGeriatrics and Rehabilitation, E.O.
Galliera Hospital, National Relevance and High Specialization, Genoa,
Department of Education, University of Genoa,
Clinical Trial Unit,
Scientific Direction, E.O. Galliera Hospital, National Relevance and High
Specialization, Genoa, Italy
While socioeconomic and lifestyle factors are thought
to be related to the health of older people, few studies explored their
relationship to frailty. We assessed the association between frailty
and socioeconomic and lifestyle factors in community-dwelling older
This was a cross-sectional survey in a population-based
sample of 542 community-dwelling aged 65 years and older subjects
living in a metropolitan area in Italy. Frailty was evaluated by means of
the FRAIL scale proposed by the International Association of Nutrition
and Aging. Basal and instrumental activities of daily living (ADL, IADL),
physical activity, sociodemographic (age, gender, marital status and
co-habitation), socioeconomic (education, economic conditions and
occupational status) and lifestyle domains (cultural and technological
fruition and social activation) were assessed through specific validated
tools. Statistical analysis was performed through logistic regression
and cluster analyses.
Impairments in ADL and IADL were significantly associated
with frailty (odds ratios[OR] and 95% Confidence Intervals[CI] 1.80,
3.40 and 4.73, 2.94
7.61, respectively) while moderate and
high physical activity were inversely associated with frailty (OR = 0.31,
0.55 and 0.26, 0.12
0.55, respectively). Being single or divorced/
separated, with low levels of education and cultural fruition were
also significantly associated with frailty. Cluster analysis revealed
six profiles based on three severity grades of frailty for both sexes,
Poster presentations / European Geriatric Medicine 7S1 (2016) S29