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P-321
The prevalence of geriatric syndroms among patients in Moscow
outpatient setting
O.N. Tkacheva
1
, N.K. Runikhina
1
, V.S. Ostapenko
1
, N.V. Sharashkina
1
,
E.A. Mkhitaryan
1,2
, Y.S. Onuchina
1
.
1
Pirogov Russian National Research
Medical University of the Ministry of Health of the Russian Federation,
Russian Gerontology Clinical Research Center,
2
Sechenov First Moscow
State Medical University of the Ministry of Health of the Russian
Federation, Moscow, Russian Federation
Objective:
There is a lack of information on the prevalence of geriatric
syndromes in Russia. The aim of our study was to evaluate the pre-
valence of excepted geriatric syndromes among patients in Moscow
outpatient setting.
Materials and methods:
The study included 1,220 patients aged 65
years and older who were followed in Moscow outpatient settings.
The average age of the patients was 74.76 ± 6.07 years and 75.5% were
women. Based on international experience, we have created a 7 = item
questionnaire to reveal main geriatric syndromes.
Results:
The highest number of positive responses were received
to the questions about the reduced vision or hearing, cognitive
dysfunction and depressed mood (58.3%, 58.2% and 46%, respectively).
Difficulty in walking noted 42% of patients, urinary incontinence
–
28.3%, fall-related injuries 21.3%, weight reduction 12.2%. Negative
answers to all questions was given by 7% of patients. More than half
of the patients (53.2%) responded positively to 3 or more questions.
Every eight patients (12.4%) responded positively to 5 or more
questions.
Conclusions:
According to the results of self-assessment we revealed
a high prevalence of geriatric syndromes in patients aged 65 years
and older in Moscow outpatient settings. More than half of these
patients need geriatric consultation. The most common geriatric
syndromes were reduced vision or hearing, cognitive dysfunction and
depressed mood.
P-322
High prevalence of cognitive impairment in elderly subjects in
primary care
O.N. Tkacheva
1
, N.K. Runikhina
1
, N.N. Yakhno
2
, E.A. Mkhitaryan
1,2
,
V.S. Ostapenko
1
, N.V. Shrashkina
1
, I.Y. Savushkina
2
.
1
Pirogov Russian
National Research Medical University of the Ministry of Health of the
Russian Federation, Russian Gerontology Clinical Research Center,
2
Sechenov First Moscow State Medical University of the Ministry of Health
of the Russian Federation, Moscow, Russian Federation
Aim:
To evaluate cognitive function in subjects >65 years consecu-
tively attending a primary care clinic in Moscow.
Methods:
The study was organized as a screening program for cogni-
tive function impairment in elderly subjects who consecutively
attended a primary care clinic irrespectively of their underling diag-
nosis. All the subjects underwent complex geriatric assessment.
Neuropsychological testing was performed using MoCA, MMSE, CDT,
TMT-A tests.
Results:
Two hundred fifty eight patients (23% male, mean age
75,6 + 5,9 years) underwent MoCA, MMSE, CDT, TMT-A evaluations.
Arterial hypertension was observed in 84% (all treated, mean BP
154 + 12/85 + 8 mmHg, systolic BP <140 mmHg in 31%), diabetes
mellitus in 23%, history of myocardial infarction or stroke was positive
in 17% and 11%, respectively. Mean score of MoCA test was 23,64 + 3,62,
MMSE test
–
27,27 + 2,29, CDR test 8,18 + 1,7, TMT-Awas 75,62 + 44,24
sec. No cognitive impairment was observed in 17%. Dementia was
found in 8%. Non-demential cognitive decline was observed in 75%
and it was mainly due to chronic cerebrovascular disease.
Conclusion:
The results obtained during this screening program
indicate high prevalence of cognitive impairment in patients who
consecutively attended a Moscow primary care clinic. Poorly control-
led arterial hypertension seems to be the leading factor for cognitive
decline in the elderly.
Area: Frailty and sarcopenia
P-323
Association of frailty with procollagen type I N propeptide in
elderly women
A. Mastaviciute, J. Kilaite, M. Tamulaitiene, V. Alekna.
Faculty of
Medicine of Vilnius University, Vilnius, Lithuania
Objectives:
The aim of this study was to investigate the association
between frailty and procollagen type I N propeptide in elderly women.
Methods:
A retrospective cross-sectional study was performed in
National Osteoporosis Centre based in Vilnius, Lithuania. Women aged
≥
60 years were included. Frailty status was defined using Fried
’
s
criteria: weakness, low walking speed, low physical activity, weight
loss, exhaustion. Participants were classified as robust, prefrail and frail
if they scored 0, 1
–
2, 3 points, respectively. Procollagen type I N
propeptide (PINP) concentration in serum was measured with Cobas
E411. Multinomial logistic regression was used to determine the
association.
Results:
The study was performed on 161 women: of them 103 (64%)
were robust, 30 (18.6%) prefrail and 28 (17.4%) frail. Robust women
group were statistically significantly youngest (mean age 69.43 ± 6.22
years) and had PINP concentration of 54.1 ± 21.2 ng/mL. Prefrail groups
’
mean age was 70.79 ± 7.92 years, PINP level
–
67.2 ± 43.1 ng/mL. The
oldest women were in frail group (75.8 ± 5.98 years) and their PINP
level was 57.1 ± 20 ng/mL. Unadjusted analysis in prefrailty versus
robust group (reference category
–
robust) showed that higher levels
of PINP were statistically significantly associated with being prefrail
(OR: 1.01, 95% CI: 1.0; 1.03; p = 0.036). After adjusting for the age, the
association between prefrailty and PINP was still statistically signifi-
cant (OR: 1.02, 95% CI: 1.0; 1.03; p = 0.04). No statistically significant
relationships were found in frailty versus robust and frailty versus
prefrailty groups.
Conclusion:
Prefrailty is associated with higher levels of procollagen
type I N propeptide in elderly women.
P-324
Frailty and pain in an internal medicine ward
R.S. Almeida
1
, M.J. Pinto
1
, S. Malaca
1
, M. Sousa
1
, J.M. Costa
1
.
1
Hospital
distrital de Santarém
–
3rd department of Internal Medicine
Introduction:
Frailty is defined as a state of decline and vulnerability
in late life, which entails a high risk of adverse outcomes [1,2].
Persistent pain is common among the elderly, with harmful
consequences [3].
Methods:
To study frailty and pain in patients admitted to an internal
medicine ward during April 2016, measured with the Tilburg Frailty
Indicator [4] and the Pain Impact Questionnaire (PIQ-6) [5]. Patients
with <65 years, with severe intellectual impairment [6] and those
who refused to participate were excluded.
Results:
From the 63 elderly patients admitted, 41 were included in
the study. The mean age was 78.7 ± 6.0 years and 70.7% of the patients
were women. There were 58.5% patients considered frail (score
≥
6).
Pain and frailty were higher in woman, but not significantly. In the
≥
80 years old group (48.8%), physical frailty and the pain impact
score were also not significantly different. A greater pain impact was
correlated with a higher frailty score (r = 0.442; p = 0.004). Patients
reported pain in 80.5%, with a mean of 58.5 ± 8.1 in the PIQ-6 score.
There was a previous ambulatory prescription of pain medication in
9,8%. During admission, 56.1% had analgesics (87.0% with paracetamol,
if needed). At discharge, 11.1% had an analgesic prescription.
Key conclusions:
Higher levels of pain were correlated with higher
levels of frailty. This emphasizes the importance of early detection
and interdisciplinary intervention, aiming to prevent vulnerability and
to reduce the incidence of complications. Hospitalization is an
opportunity to intervene but there is still much to be done in raising
awareness of health professionals.
Poster presentations / European Geriatric Medicine 7S1 (2016) S29
–
S259
S114