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Introduction:
Frailty can be defined as a state of increased vulnera-
bility, with mutually exacerbating cycle of negative energy balance,
sarcopenia, and diminished strength and tolerance for exertion. Frailty
and malnutrition are frequent conditions in elderly.
Objective:
Study the relationship between malnutrition and frailty in
elderly.
Methods:
A cross-sectional study with 66 hospitalized elderly
patients (>65 years). Frailty was defined by the 9-point Clinical
Frailty Scale (CFS). Nutritional status was analyzed by Mini-nutritional
Assessment-Short Form (MNA-SF, >12 well-nourished, 7
–
12 under
risk, <7 malnourished), anthropometric measures (body mass index,
BMI; ideal adequacy of weight by Lorentz formula; mid-arm
muscle circumference
–
MUAMC, <70% severe, 70
–
80% moderate and
80
–
90% mild malnutrition) and albumin (normal >3 g/dL). The risk of
nutrition-related complications was calculated by Geriatric Nutritional
Risk Index (GNRI, >98 no risk, <98 under risk). Categorization in two
groups: G1 with CFS
≤
6 (normal to moderately) and G2 with CFS >7
(severely frail).
Results:
(1) There were included 38 patients in G2, with mean age of
82.1 ± 6.3 years (vs 84.4 ± 5.2; p = 0.116). (2) The mean MNA-SF in G2
was 8.2 ± 3.2 (vs 12.2 ± 2.5; p < 0.01), 44% with MNA-SF <7 (p < 0.001).
(3) G2 had lower BMI (22.3 ± 3.3 vs 25.4 ± 4.7; p = 0.003), lower
adequacy of weight (101.1 vs 112.9%; p = 0.011), and lower MUAMC
(76.8 ± 13.3 vs 84.5 ± 14.6 cm
2
; p = 0.053). (4) G2 had more hypoalbu-
minaemia (52 vs 21.6%; p = 0.046). (5) G2 had lower GNRI (87.4 ± 15.5
vs 98.5 ± 13.4; p = 0.005) and 52.9% were already at risk of malnutri-
tion-complications. (<98, p = 0.185).
Conclusions:
Because of the role of nutritional deficiency in the
development of frailty, it is important to provide good nutritional
support, avoiding health status deterioration and disability in older
people.
P-340
Instrumented 6-minutes walk test, an approach to improve the
traditional test
A. Galán-Mercant
1,2
, T. Tomás
3
, B. Fernandes
3
.
1
University of Jaén,
2
IBIMA Institute, University of Malaga, Spain;
3
Escola Superior Tecnología
de Saude de Lisboa, Portugal
Introduction:
Exercise testing is frequently used to assist clinicians in
assessing prognosis and evaluating response to treatment. The 6-min
walk test is a standardized test of functional exercise capacity.
Objectives:
The aim of the present study was to identify and describe
the anthropometric characteristics, gait velocity and instrumented
6-min walk test with kinematics parameters from inertial sensor
during the test in a Portuguese population of subjects over 65 years.
Methods:
They were measured variables related with anthropomet-
rics, the 6-min walk test and kinematics variables in the 6-min walk
test related with accelerations and angular velocity.
Results:
The results were; six minutes walk (359,26 ± 107.49 meters),
initial heart rate (72,95 ± 7,74BPM), final initial heart rate (80,58 ±
13,86 BPM), initial systolic blood pressure (148,42 ± 21,25 mmHg),
final systolic blood pressure (164,26 ± 24,49 mmHg), initial diastolic
blood pressure (75,63 ± 11,04 mmHg), final diastolic blood pressure
(77,00 ± 9,52 mmHg), gait velocity (1,04 ± 0,37 m/s), max rotation rate
X (1,05 ± 0,36 rad/s), min rotation rate X (
−
0,82 ± 0,33 rad/s), max
rotation rate Y (2,63 ± 0,96 rad/s), min rotation rate Y (
−
1,69 ± 0,81 rad/
s), max rotation rate Z (1,03 ± 0,33 rad/s), min rotation rate Z (
−
1,12
± 0,38 rad/s), max acceleration X (0,77 ± 0,37 m/s
2
), min acceleration X
(
−
0,91 ± 0,44 m/s
2
), max acceleration Y (0,53 ± 0,23 m/s
2
), min accel-
eration Y (
−
1,25 ± 0,70 m/s
2
), max acceleration Z (0,49 ± 0,14 m/s
2
),
min acceleration Z (
−
0,96 ± 0,34 m/s
2
).
Conclusions:
The only one outcome in 6-min walk the test (total
distance in meters), could be complemented with inertial sensor
information. This new complement could be interesting in order to
understand other dimensions in the 6-minwalk or identify changes in
function and results in the test after a program to improve physical
fitness.
P-341
Fatih province
−
Geriatric Study: fragility and contributing factors
in old population living the community
S. Gonultas
3
, A. Ersoy
3
, G. Bahat
1
, C. Kilic
1
, F. Tufan
1
, S. Avc
ı
2
,
M.A. Karan
1
.
1
Division of Geriatric, Department of Internal Medicine,
Faculty of Istanbul Medicine, Istanbul University,
2
Division of Geriatric,
Department of Internal Medicine, Faculty of Cerrahpasa Medicine,
Istanbul University,
3
Faculty of Istanbul Medicine, Istanbul University,
Istanbul, Turkey
Aim:
In this abstract, we aimed to investigate fragility prevalence and
contributing factors among the old population living in Fatih/Istanbul
province.
Material and methods:
Age range of 60
–
101were taken into the study.
The fragility screened with FRAIL-questionnaire, functional capacity
measurement with KATZ-Activities-of-Daily-Living-Scale(ADL) and
LAWTON-BRODY-Instrumental Activities
–
of-Daily Living Scale (IADL),
quality of life measurement with EQ5D-questionnaire, cognitive
status with Mini
–
Cog-test, depression with GDS-SF, malnutrition with
MNA-SF, balance and gait with Romberg-test and postural-instability-
test, were evaluated accordingly. We measured muscle mass with
bioimpedance analysi s(TANITA-BC532). We evaluated muscle mass
using Baumgartner index (skeletal muscle kg/length
2
). According to
our, lowmuscle mass(young adult average-2SD) and muscle threshold
values national data, low muscle mass values are <9.2 kg/m
2
vs
7.4 kg/m
2
; <32 kg vs <22 kg in men and women respectively. We
defined sarcopenia as decrease in sarcopenic muscle mass and muscle
function (muscle strength/OYH) as stated in EWGSOP definition.
Obesity diagnosis is evaluated using two alternative method advised
in literature:fat percentage >=60 percentile among old case population
values (Zoico methodology) or BMI >=30 kg/m
2
(WHO definition).
Findings: We included 204 old cases(94 male
–
110 female). Average
age:75,4 ± 7,3 years.30.4% of the cases were normal,42.6% were pre-
frail and 27% were frail. There significant differences in these groups in
terms of age/number of diseases/drugs/hand grip strength/daily life
activities/EGYA/cognitive state/SÇT (p = 0.001) /MNA/ GDS/Eq-5D
score and health state subjective scoring (p < 0.001); BMI (p = 0.032),
OYH (p = 0.03), BIA-fat (p = 0.021) and muscle mass (p = 0.019). On the
other hand, there were no significant differences in calf diameter
(p = 0.25, visceral fat level (p = 0.71). While there were significant
differences between the fragility groups, in terms of presence of
malnutrition/fear of falling/UI/chronic pain/Romberg
’
s sign/postural
instability/ambulation level/presence of depression (p < 0.001)/
dementia (p = 0.001)/falling in past year (p = 0.011) and sex (p =
0.004), there were no significant differences in presence of diabetes
(p = 0.90), hypertension (p = 0.065, fecal incontinence (p = 0.10). In
regression analysis, independent factors to fragility were (dependent
variable fragility (robust vs prefrail + frail), independent variables:
age, sex, disease and drug number, muscle strength, egya and EQ-5D
scores; cognitive dysfunction-depression, MN, falls, presence of
chronic pain) drug number (OR = 1.24, p = 0.036), cognitive dysfunc-
tion (OR = 0.3, p = 0.016), EQ-5D (OR = 1.53, p = 0.017).
Results:
Our study is a strong study in multiple factors are taken into
account regarding fragility. Our results indicate that multiple drug
usage, cognitive-dysfunction and low-life-quality perception are
related major factors regarding fragility.
P-342
Comprehensively preventive approach against multi-dimensional
frailty in the elderly: impact of social engagement
K. Iijima
1
, T. Tanaka
2
, K. Takahashi
1
, K. Toba
3
, K. Kozaki
4
, M. Akishita
2
.
1
Institute of Gerontology, The University of Tokyo,
2
Department of
Geriatric Medicine, The University of Tokyo Hospital,
3
National Center
for Geriatrics and Gerontology,
4
Department of Geriatric Medicine,
Kyorin University School of Medicine
Introduction:
Frailty is accelerated by sarcopenia, age-related muscle
loss, and is largely overlapping geriatric conditions upstream of the
disabling cascade. These multi-dimensional frailty are affected from
Poster presentations / European Geriatric Medicine 7S1 (2016) S29
–
S259
S119