European Geriatric Medicine - Supplement 1 - Volume 7 - October 2016

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physical function, sense of competence and resource utilizationwill be
studied (at baseline, six months and one year).
Key conclusions: In vascular dementia, as in other chronic conditions
the burden of disease arises more from disability than from mortality.
Interventions designed to decrease disease burden, promote coping
and adaptation, and improve health and social services use are
warranted. With the present study we pretend to contribute to the
development of scientifically based effective preventive strategies
regarding vascular dementia.
P-094
Evolution of cognitive function after transcatheter aortic valve
implantation
D. Bertschi 1, S. Stortecky2, C. Zuber1, A. Moser1,3, M. Zwahlen3,
P. Wenaweser 2, S. Windecker2, T. Carrel, A. Stuck1, A. Schoenenberger1.
1Department of Geriatrics, Bern University Hospital, and University of
Bern, 2Department of Cardiology, Swiss Cardiovascular Center Bern,
Bern University Hospital, 3Institute of Social and Preventive Medicine,
University of Bern, Department of Cardiovascular Surgery, Bern University
Hospital, Switzerland
Background: This study aimed to assess the evolution of cognitive
function after transcatheter aortic valve implantation (TAVI). Previous
smaller studies reported conflicting results on the evolution of
cognitive function after TAVI.
Methods: In this prospective cohort, cognitive function was measured
in 229 patients ≥70 years using the Mini Mental State Exam (MMSE)
before and 6 months after TAVI. Cognitive deterioration or improve-
ment was defined as change ≥3 points decrease or increase in the
MMSE score between baseline and follow-up.
Results: Cognitive deterioration was found in 29 patients (12.7%).
Predictive analysis using logistic regression did not identify any
statistically significant predictor of cognitive deterioration. A review
of individual medical records in 8 patients with a marked MMSE
score decrease ≥5 points revealed specific causes in six cases (post-
interventional delirium in two; post-interventional stroke, progressive
renal failure, progressive heart failure, or combination of pre-existing
cerebrovascular disease and mild cognitive impairment in one each).
Among 48 patients with impaired baseline cognition (MMSE score
<26 points), 18 patients (37.5%) cognitively improved. The pre-
interventional aortic valve area (AVA) was lower in patients who
cognitively improved (median AVA 0.60 cm 2) as compared to patients
who did not improve (median AVA 0.70 cm 2) (P = 0.01).
Conclusions: This is the first study providing evidence that TAVI results
in cognitive improvement among patients who had impaired pre-
procedural cognitive function, possibly related to hemodynamic
improvement in patients with very severe aortic stenosis. Our results
confirm that some patients experience cognitive deterioration
after TAVI.
P-095
Correlation between intensity of memory complaints and actual
memory disorder
A. Besozzi 1,2, E. Spitz2, M. Perdrix1, M. Villaume1,
C. Perret-Guillaume 1,2. 1CMRR CHRU Nancy; 2Laboratoire APEMAC
EA4360 Université de Lorraine
Objectives: Memory complaints (MCs) are experienced by a large
proportion of older adults and are often a source of distress and worry.
Because of the perceived threat of Alzheimer’ s disease, MCs are known
to be associated with depression, anxiety and poor quality of life.
Although the literature is unclear about evolution of patients with
MCs, there is growing evidence that suggests that MCs are associated
with an increased risk of dementia. The importance of MCs is
furthermore reflected in the new diagnostic criteria proposed for
early AD [1]. The Common Sense Model [2] help us to understand the
memory problems perceptions of people with MCs and how they
manage with their difficulties.
Methods: This pilot study aims to examine correlations between the
score at the Illness Perception Questionnaire-Memory (IPQ-M) and
the actual memory disorder assessed by the Free and Cued Selective
Reminding Test (FCSRT). Forty-nine persons were recruited at the
Memory Center of Nancy, France (mean age: 70 years; sex ratio: 31
female).
Results: Results show that the memory problems perceptions are
better (less negative) with ageing and high educational level. We
found a significant positive correlation between emotional impact
at the IPQ-M and the free recall at the FCSRT. That could interpreted
as an effect of anxiety on retrieval process. There is no other link
between memory problems perceptions and actual memory disorder.
The emotional impact of memory problems are seems to influence
cognitive performances.
Conclusion: These results pointed the importance of psychoeducation
and individualized care in the diagnosis process of memory disorders.
References
1. Dubois B. et al. (2007). Research criteria for the diagnosis of
Alzheimer’ s disease: revising the NINCDS-ADRDA criteria. Lancet
Neurology, 6(8), 734– 746.
2. Leventhal H., Brissette I. & Leventhal E.A. (2003). The common-
sense model of self regulation of health and illness. In Cameron L.D.
& Leventhal H. (Eds.), The self-regulation of health and illness
behaviour. New York: Routledge, Taylor & Francis Groupe.
P-096
My life story
E. Borizovski, M. Sambuchi, A. Parzy, J. Dodard, C. Farjon. Geriatrician,
Psychologist, Occupational Therapist, Quality Assistant, Coordinator Nurse
Introduction: “My Life Story” is a concept which involves making a
book of one’s life, which allows seniors in nursing homes to
reappropriate and revisit their history and memories. This booklet
contains the life course of each resident and has for the purpose a long-
term study of behavioral and moods disorders, in the practical
application of non-drug treatments.
Methods: Each book is created during a weekly session. The resident
himself or one of his relatives, (if the resident presents demential
disabilities or psychiatric disorders), evoke his life based on specific
events illustrated by personal photos that he has preselected. This
booklet is established two months after arrival in nursing home
while residents get their benchmarks. This study analyses three
groups of residents: -“Placebo”, - “Demented” –“Psychiatric ”; Under
three different conditions: -With booklet and an hour aweek personal
accompaniment, -With booklet and without accompaniment,
-Without booklet and without accompaniment.
Results: The qualitative results, verbalized or observed data, will allow
working on the resident’s representations and interpretations on some
aspects of their lives, but also how they lived them. The quantitative
results, which study the decrease in medical prescriptions, as well as
mood and behavioral disorders will demonstrate the positive effect or
not of this booklet.
Conclusions: Improvements will be made in multidisciplinary group
such as recording interviews by video to investigate objectively the
exchange time and the different expressions between the resident and
his family or nursing team.
P-097
Incidence of dementia in depressed patients – evidence based
review
I. Calvinho1, S. Pessoa1, J. Correia1, M. Galo1, J. Caçoilo1, C. Bento1.
1Unidade de Saúde Familiar Oriente, Lisbon, Portugal
Introduction: Depression and dementia are complex frequent
syndromes with features that overlap each other. Considering the
morbidity of dementia and the preventability and treatability of
depression, the aim of this study is to review the evidence for the
association between depression and incidence of dementia.
Poster presentations / European Geriatric Medicine 7S1 (2016) S29–S259 S53