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Conclusions:

In conclusion patients with neuropsychiatric symptoms

are more likely to have MND and to a lesser extent MNDA.

P-101

The impact of disability on long-term mortality among older men

aged 80 years and over with different cognitive status: results from

longitudinal older veterans study

Ming-Yueh Chou

1,3

, Chih-Kuang Liang

1,2,3

, Mei-Chen Liao

1

,

Hsiu-Chu Shen

1,2

, Yu-Teh Lin

1,2

, Hing-Chung Lam

1

.

1

Center for

Geriatrics and Gerontology,

2

Division of Neurology, Department of

Medicine, Kaohsiung Veterans General Hospital,

3

Aging and Health

Research Center, National Yang Ming University, Taiwan

Objective:

To evaluate the impact of disability on long-term mortality

among older men aged 80 years and over with different cognitive

status living in the retirement community.

Method:

This prospective cohort study enrolled older men aged 80

and older living in Gangshan Veterans Home (n = 305). Subjects with

confirmed diagnosis of dementia were excluded. All participants

were evaluated with comprehensive geriatric assessment including

socio-demographic data, geriatric syndromes, activities of daily living

measured by Barthel index and cognitive function assessed by Mini-

Mental State Examination (MMSE). MMSE was categorized into groups

with normal, mild, or moderate-severe cognitive impairment.

Disability was classified as Barthel index less than 85. The main

outcome measure was all-cause mortality over 3-year follow-up. Cox

proportional hazards model was conducted to examine the association

between cognitive function, disability and increased risk for mortality,

after controlling for sociodemographic characteristics and geriatric

syndromes.

Results:

During the 3 year follow-up periods, 76 participants died.

The mortality risk was signi

fi

cantly associated in disability and mild

cognitive dysfunction category [adjusted hazard ratio (HR): 2.850,

p = 0.008] and in disability and moderate cognitive dysfunction

category (adjusted HR: 5.019, p < 0.001)after adjustment for potential

confounders. But the association of cognitive impairment and

mortality was not observed in elderly without disability.

Conclusions:

Our results showed that mild and moderate-to-severe

cognitive impairments were strongly mortality predictive factors

among subjects with physical disability. However, no significant

mortality risk was identified among subjects with physical disability

without cognitive impairment and those with mild-to-severe cogni-

tive impairment without physical disability.

P-102

Prospective evaluation of the effects of group psychotherapy

among caregivers of dementia patients: a study protocol

U. Cintosun, M.I. Naharci, E. Kalinkilic, E. Bozoglu, H. Doruk.

Division of

Geriatrics, Gulhane Military Medical Academy, Ankara, Turkey

Introduction:

In addition to being a serious health issue that is more

frequently encountered worldwide, dementia is becoming a social

problem. Caregivers of those, may have to handle psychological, social

and financial issues in addition to the patient

s issues.

Objective:

Here we define the protocol of a study that evaluates a

group psychotherapy intervention developed for caregivers of demen-

tia patients. Our first hypothesis is that group psychotherapy

intervention will diminish the burden on the caregiver of dementia

patient. Our second hypothesis is that reducing the burden on the

caregiver will positively affect the clinical progress of the dementia

patient.

Method:

Caregivers of dementia patients will be included. Three

sessions (at the start, first and second weeks) will be held to inform

all caregivers based on current guidelines concerning the progress

of dementia, the probable problems, and their solutions. Caregivers

will be divided into three groups based on the dementia subtype.

Moreover, the subjects will be categorized according to their

participation in the psychotherapy intervention (no participation,

control group 1; 1 or 2 sessions participation, control group 2;

participation to all three sessions, study group). The characteristics of

patients and their caregivers will be recorded. The stress levels of

the caregivers prior to group therapy, at 1, 3 and 12 months after

the therapy will be evaluated using Zarit Caregiver Burden Interview,

Beck Depression Inventory and Beck Anxiety Inventory. The effects of

group psychotherapy on depression in dementia patients will be

assessed by Cornell scale for depression in dementia.

P-103

Prevalence and predictors of cognitive impairment among older

adults across Europe based on SHARE database

J. Lourenço

1,2,3

, A. Serrano

1

, A. Santos-Silva

4

, M. Gomes

4,5

, C. Afonso

2

,

P. Freitas

6

, C. Paúl

3,7

, E. Costa

4

.

1

USF Pedras Rubras, Maia,

2

Faculty of

Nutrition and Food Sciences, University of Porto,

3

CINTESIS, University of

Porto,

4

UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto,

5

I3S - Institute of Investigation and Innovation in Health, University of

Porto,

6

Faculty of Medicine of University of Porto, Centro Hospitalar São

João, E.P.E.,

7

ICBAS, University of Porto, Porto, Portugal

Objectives:

Increased life expectancy is associated with high preva-

lence of chronic non communicable diseases, including cognitive

decline and dementia. Cardiovascular risk factors have been associated

with cognitive decline. This works aims to evaluate the prevalence

and the predictors of cognitive impairment, with a special focus on

cardiovascular risk factors, across Europe.

Methods:

Data fromparticipants inwave 4 of SHARE (Survey of Health,

Ageing, and Retirement in Europe) database were used. Perceived

memory, verbal fluency and numeracy were used to access cognitive

function. Clinical and sociodemographic variables were evaluated as

potential predictors. Age and gender standardized prevalence rates of

cognitive impairment were calculated for 16 European countries.

Results:

From 58,489 participants on wave 4, we selected those over

50 years old, who responded to all questions included in this work.

Accordingly, we included 33,580 individuals (65.4 ± 10.0 years

old, 56.4% females). The prevalence of cognitive impairment was

28.02%, 27.89% and 20.75% for perceived memory, verbal fluency and

numeracy, respectively, in the 16 evaluated countries. Age, years of

education, smoker or former, more than 2 chronic diseases, diabetes or

hyperglycemia, high blood cholesterol, heart attack and stroke were

independent variables associated with perceived memory, verbal

fluency and numeracy. We also found an independent association high

blood pressure and body mass index with perceived memory and ver-

bal fluency; and female gender with perceived memory and numeracy.

Conclusions:

Prevalence of cognitive impairment showed accentu-

ated disparities between countries. Predictors of cognitive impairment

were multifactorial, including factors that can be prevented or treated,

namely cardiovascular risk factors.

P-104

The MINDMAP consortium and its geriatric perspective on

promoting mental well-being and healthy ageing in cities

U. Dapp

1

, L. Neumann

1

, W. von Renteln-Kruse

1

, M. Avendano-Pablon

2

,

F. van Lenthe

3

, for the MINDMAP Consortium.

1

Albertinen-Haus, Centre

of Geriatrics and Gerontology, Scientific Department at the University of

Hamburg, Germany;

2

Department of Social Science, Health and Medicine,

King

s College, London;

3

Department of Public Health, Erasmus University,

Rotterdam

Introduction:

Major depressive disorder, dementia, anxiety disorders,

and substance abuse affect a substantial part of the European older

population. Over 70% of Europeans reside in cities, and this percentage

will increase in the next decades. Urbanization and ageing have

enormous implications for public mental health. Cities pose major

challenges for older citizens, but also offer opportunities for the design

of policies, clinical and public health interventions that promote

mental health.

Methods:

The overall aim of the MINDMAP project (2016

2019) is to

identify the opportunities offered by the urban environment for the

promotion of mental wellbeing and cognitive function of older

Poster presentations / European Geriatric Medicine 7S1 (2016) S29

S259

S55