137 / 290
show improvement. Our model was validated in an external popu-
lation of adults 80+. The model with CRP and BNP had higher risk of
cardiovascular mortality [HR(95%CI) = 5.1(2.2
–
11.4)] and had a better
predictive capacity compared with baseline model [HR(95%CI) = 2.2
(1.2
–
4.0)].
Conclusion:
We have developed a new score that may be used as an
instrument to predict the risk of total and cardiovascular mortality in
the older adults.
P-382
Testing the acceptance of a community-based, technology-
supported service for detecting and preventing frailty
L. Van Velsen
1
, M. Illario
2
, A. Renzullo
2
, P. Riccio
2
, M. Vollenbroek-
Hutten
3
.
1
Roessingh Research and Development, Enschede, the
Netherlands;
2
Federico II University, Naples, Italy;
3
University of Twente,
Enschede, the Netherlands
Introduction:
Frailty is a condition that affects many older adults and
for which few preventive services are available. Within the PERSSILAA
project, we developed a service for preventing frailty in community
dwelling older adults via physical and cognitive training, and by
educating them about healthy nutrition, either in the older adults
’
neighborhood or online.
Methods:
We tested the acceptance of this service among 46 older
adults and 42 stakeholders (geriatricians, policy makers, etc.) in the
Netherlands and Italy. They were shown an animation explaining
the service, and were asked questions about their intention to use, its
perceived value, and their (dis)likes.
Results:
Older adults
’
intention to use scored a mean of 3.78 (st dev
1.21; five-point scale). In the Netherlands 75% of the older adults
preferred the online services, in Italy 25%. Healthcare professionals
awarded a mean of 4.10 (st dev .96; five-point scale) when rating the
usefulness of the service; other stakeholders gave an average score of
4.00 (st dev .74). Oftenmentioned positive points were that the service
provides early detection of health issues, allows for tracking one
’
s
health, and can combat loneliness. Negative points included that the
service may be considered patronising, and that some older adults lack
digital skills or access.
Conclusion:
Frailty prevention services that utilise local facilities
and online technology have a high chance of success, as long as they
provide freedom of choice to the older adult and are integrated
with ICT training in the community, providing the added benefit of
socialization.
P-383
Improvement in Quality of life (QoL) of two cohorts of frail older
people at three and six months after hospitalization
O. Vazquez
1
, C. Roqueta
1
, E. de Jaime
1
, R. Miralles
1
, O. Cunillera
2
,
A. Pont
2
, M. Ferrer
2
, D. Sanchez
1
, P. Garcia
1
, A. Renom
1
.
1
Geriatrics
Department. Centre Forum. Hospital del Mar. Parc de Salut Mar.
Barcelona,
2
Health Services Research Unit. IMIM-Hospital del Mar.
Barcelona Biomedical Research Park. Spain
Introduction:
This study aims to compare the results of QoL using The
Nottingham Health Profile (NHP) of two cohorts of frail older people
who were discharged from the hospital to either a postacute care unit
(PCU) or home.
Methods:
Prospective observational study of 75 patients hospitalized
in an acute hospital ward, aged
≥
65, who fulfilled the inclusion
criteria: inability to transfer from the chair/bed, inability towalk alone,
altered mental status, absence of severe dementia/terminal disease
and availability of an informal caregiver. Patients could choose
between admission to PCU or discharge home. At discharge, 3 and 6
months later we gathered information on QoL using the NHP(range
0
–
100, with higher scores indicating worse QoL) and each of its six
dimensions. Improvement of QoL was defined as a decrease in the
score of NHP or/and an effect size (ES)
≥
0.8 (large change).
Results:
42 patients were admitted to PCU while 35 were discharged
home. Participants were comparable in terms of functional, cognitive
and social variables studied. At 3 months we found a significant
improvement in the social isolation dimension of NHP in PCU group
(31.4 ± 29.4 vs 48.4 ± 24.5, p = 0.04, ES:1.08). At six month we found
significant improvements in the global NHP score (32.1 ± 21.8 vs
54.5 ± 16.2, p = 0.041, ES:1.16) and in the following dimensions:
energy (33.3 ± 31.4 vs 70.3 ± 30.9, p = 0.033, ES:1.18), social isolation
(16.0 ± 15,7 vs 35.5 ± 16,6, p = 0.033, ES:1.2) and emotional(25.5 ± 28.7
vs 60.6 ± 26.3, p = 0.014, ES:1.27).
Key conclusions:
Patients admitted in PCU after hospital discharge,
might have better quality of life after three and six months compared
with those who were discharged home.
P-384
Sufficient levels of 25-hydroxyvitamin D and protein intake
required to increase muscle mass in sarcopenic older adults
–
The
PROVIDE study
S. Verlaan
1,2
, A.B. Maier
3,4
, J.M. Bauer
5
, I. Bautmans
6
, S. Wijers
1
,
C. Sieber
7
, Y. Boirie
8
, T. Cederholm
9
.
1
Nutricia Research, Utrecht,
2
VU
University medical center,
3
VU University, Amsterdam, The Netherlands;
4
University of Melbourne, Australia;
5
Carl von Ossietzky University,
Oldenburg, Germany;
6
Vrije Universiteit Brussel (VUB), Brussels, Belgium;
7
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany;
8
Clermont Université, Clermont-Ferrand, France;
9
Uppsala University
Hospital, Sweden
Objectives:
Inadequate nutritional intake and altered response of
aging muscles to anabolic stimuli from nutrients contribute to the
development of sarcopenia. Nutritional interventions show inconsist-
ent results in sarcopenic older adults, which might be influenced by
their basal nutritional status. The objective was to test if baseline
serum 25-hydroxy vitamin D (25(OH)D) concentrations and dietary
protein intake influenced changes in muscle mass and function in
older adults who received nutritional intervention.
Methods:
Post-hoc analysis of the PROVIDE study was performed to
assess whether baseline serum 25(OH)D levels and dietary protein
intake influenced the intervention effects of the 3 month supplemen-
tation with vitamin D and leucine-enriched whey protein medical
nutrition drinks among 380 sarcopenic older adults. A baseline serum
concentration of 50 nmol/L 25(OH)D and baseline dietary protein
intake of 1.0 g/kg/d were used as cut offs to define groups.
Results:
Participants with higher baseline 25(OH)D concentrations
and dietary protein intake had, independent of other determinants,
greater gain in appendicular muscle mass in response to the nutri-
tional intervention. There was no effect modification of baseline 25
(OH)D status or protein intake on change in chair-stand test.
Conclusion:
Sufficient baseline levels of 25(OH)D and protein intake
may be required to increase muscle mass as a result of a 3 month
intervention with vitamin D and leucine-enriched whey protein
supplements in sarcopenic older adults. This suggests that current cut-
offs in the recommendations for vitamin D and protein intake should
be considered the
“
minimum
”
for adults with sarcopenia in strategies
to attenuate muscle loss.
P-385
Hand tactile discrimination, social touch and frailty criteria in
elderly people: a cross sectional observational study
A. Vieira
1,4
, D. Nogueira
2
, E. Reis
3
, M. Rosado
1
, M. Nunes
4
, A. Castro-
Caldas
4
.
1
Alcoitão School of Health Sciences, Physiotherapy Department,
Rua Conde Barão, Alcoitão 2649-506,
2
Speech Therapy Department,
Alcoitão School of Health Sciences, Rua Conde Barão, Alcoitão 2649-506
Alcabideche,
3
Business Research Unit, ISCTE-University Institute of Lisbon,
Av
a
das Forças Armadas,1649-026,
4
Institute of Health Sciences
–
Catholic
University of Portugal, Palma de Cima, 1649-023 Lisbon, Portugal
Objectives:
Frailty is a common syndrome among elderly and sensory
decline may exacerbate functional decline. The hand function, the
manual dexterity, the performance of the daily living skills and the
social interactions are determined, in a large degree, by sensory
integrity. However, hand tactile sensory deterioration has been little
Poster presentations / European Geriatric Medicine 7S1 (2016) S29
–
S259
S131