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used to assess e.g. age, sex, and subjective achievement of the Dutch

physical activity guideline, defined as 30 minutes of moderate physical

activity for at least 5 days. Physical activity was measured using 7-day

accelerometry. Muscle-related parameters included absolute and

relative muscle mass, handgrip strength and gait speed. Data analysis

was stratified by age.

Results:

192 (80.9%) participants reported to meet the recom-

mended Dutch physical activity guideline whereas this was actually

the case in 50 (21.2%) participants. The association of I-PA with

muscle mass, handgrip strength and gait speed was age dependent.

In middle-aged adults, I-PA was not associated with muscle mass,

handgrip strength or gait speed. In older adults, I-PAwas significantly

associated with handgrip strength and gait speed, but not with muscle

mass.

Conclusions:

Physical activity should be measured objectivity. The

complex interrelation between physical activity, muscle measures and

physical performance is highly dependent on age.

P-379

Lack of knowledge and diagnostics hinders the implementation of

sarcopenia in daily practice

E.M. Reijnierse

1

, M.C. Trappenburg

1,2

, M.A.E. de van der Schueren

3,4

,

M. Doves

5

, C.G.M. Meskers

6

, A.B. Maier

7,8

.

1

Department of Internal

Medicine, Section of Gerontology and Geriatrics, VU University Medical

Center, Amsterdam,

2

Department of Internal Medicine, Amstelland

Hospital, Amstelveen,

3

Department of Internal Medicine, Section

Nutrition and Dietetics, VU University Medical Center, Amsterdam,

4

Department of Nutrition, Sports and Health, Faculty of Health and Social

Studies, HAN University of Applied Sciences, Nijmegen,

5

Institute of

Human Movement Studies, Faculty of Health Care, University of Applied

Sciences Utrecht,

6

Department of Rehabilitation Medicine, VU University

Medical Center,

7

Department of Human Movement Sciences, MOVE

Research Institute Amsterdam, VU University, Amsterdam, The

Netherlands;

8

Department of Medicine and Aged Care, Royal Melbourne

Hospital, University of Melbourne, Melbourne, Australia

Objectives:

Sarcopenia is an emerging clinical challenge in an ageing

population and is associated with negative health outcomes.

Healthcare professionals play a key role in diagnosing and managing

sarcopenia. This study aimed to assess the current state of know-

ledge regarding the definition of sarcopenia, strategy diagnosing it

and involved collaborating healthcare professionals among a group

of Dutch healthcare professionals attending a lecture cycle on

sarcopenia.

Methods:

The Sarcopenia Road Show comprised lectures and work-

shops on the pathophysiology of sarcopenia in one session, influencing

factors and respective interventions at multiple locations in the

Netherlands in 2015. Attending health care professionals were asked

to complete a questionnaire (n = 223) before, directly after and after

five months.

Results:

69.7% of healthcare professionals stated to know the

definition of sarcopenia and 82.6% had treated patients with sus-

pected sarcopenia. Only 21.4% indicated to know how to formally

diagnose sarcopenia; 47.5% used their clinical view. If diagnostic

measures were used, handgrip strength was the most frequent one

(33.9%). Five months after attendance, muscle mass was measured

by 13.9%, handgrip strength by 50.6% and gait speed by 54.4%.

Bottlenecks during the implementation of diagnosing sarcopenia

were experienced by 67.1% participants; lack of knowledge among

collaborating healthcare professionals, the acquisition of equipment

and time constrains to perform the diagnostic tests were most often

reported.

Conclusions:

The concept of sarcopenia is familiar to most and diverse

healthcare professionals, however lack of formal knowledge hinders

the implementation of diagnostics and intervention of sarcopenia in

daily practice; collaboration should be improved.

P-380

The European Working Group on Sarcopenia in Older People

(EWGSOP) definition of low muscle mass is associated with

functionality and nutritional status in residents of a nursing home

A. Tufan

1

, G. Bahat

2

, H. Ozkaya

3

, D. Taşc

ı

oğlu

2

, F. Tufan

2

, B. Saka

2

,

S. Akin

4

, M.A. Karan

2

.

1

Department of Internal Medicine, Division of

Geriatrics, Marmara University Hospital,

2

Department of Internal

Medicine, Division of Geriatrics, Istanbul Medical School,

3

Istanbul

Metropolitan Municipality, Department of Health and Social Services,

Kay

ı

şdagi Darulaceze Ministry, Istanbul,

4

Department of Internal

Medicine, Division of Geriatrics, Erciyes Medical School, Kayseri, Turkey

Objectives:

To determine the prevalence of low muscle mass(LMM)

and the relationship between sarcopenic LMM with functionality and

nutritional status as defined using the European Working Group on

Sarcopenia in Older People(EWGSOP) criteria among male residents in

a nursing home.

Methods:

Male residents aged >60 years of a nursing home located in

Turkey, were included in our study. Their bodymass index(BMI) kg/m

2

,

skeletal muscle mass(SMM)kg/m

2

, and skeletal muscle mass index

(SMMI) kg/m

2

were calculated. Functional status were evaluated

with Katz activities of daily living(ADL) and Lawton Instrumental

Activities of Daily Living(IADL). Nutritional assessment was performed

using the Mini Nutritional Assessment(MNA). The number of drugs

taken and chronic diseases were recorded.

Results:

One hundred fifty-seven male residents were enrolled into

the study. Their mean age was 73.1 ± 6.7 years with mean ADL score

of 8.9 ± 2.0 and IADL score of 8.7 ± 4.6. One hundred twelve (71%)

residents were aged >70 years. Thirty-five (23%) men had sarcopenic

muscle mass in group aged >60 years, and twenty-eight(25%) subjects

in the group aged >70 years. MNA scores were significantly lower in

sarcopenic residents compared with nonsarcopenic males(17.1 ± 3.4

vs. 19.6 ± 2.5, p = 0.005). BMI was significantly lower in the sarcope-

nic group compared with the nonsarcopenic subjects (19.6 ± 2.7vs.

27.1 ± 4.1, p < 0.001). ADL scores were significantly different between

sarcopenic and nonsarcopenic subjects in those aged >70 years

(8.1 ± 2.6 vs. 9.1 ± 1.6, p = 0.014).

Conclusions:

There is a strong association of sarcopenic muscle mass

with functionality and nutritional status within the nursing home

setting using the EWGSOP criteria with Turkish normative reference

cut-off values.

P-381

Validation of a new mortality risk prediction model for people 65

years and older in northwest Russia: the crystal risk score

A. Turusheva

1

, E. Frolova

1

, B. Vaes

2

, E. Hegendoerfer

2

, J.M. Degryse

2

.

1

Russia,

2

Institut de Recherche Santé et Société, Université Catholique

de Louvain, Brussels, Belgium

Introduction:

Prediction models of adverse outcomes for older adults

may help physicians make decisions about screening, diagnosis

and treatment. Neither the classical phenotype, nor the accumulated

deficit model and self-report approach of frailty appeared to be valid in

our cohort. This study aims to develop a risk score that predict short-

term mortality and perform its internal and external validations.

Methods:

In a population-based prospective cohort study of 611

community-dwelling individuals 65+, mortality risks over 2.5 years

follow-up were determined based on the results obtained from

anthropometry, medical history, physical performance tests, spirom-

etry and laboratory tests. C-statistic, Risk Reclassification analysis,

Integrated Discrimination Improvement analysis, decision curves

analysis, internal validation and external validation were performed.

Results:

Older adults were at higher risk for mortality [HR(95%CI) = 4.5

(3.7

5.5)] when two or more of the following components were

present: poor physical performance, low muscle mass, poor lung

function, and anemia. If anemia was combined with high C- reactive

protein (CRP) and high B-type natriuretic peptide (BNP) was added

the HR(95%CI) was higher (5.8(4.7

7.1)) even after adjusting for age,

sex and comorbidities, but reclassification measurements did not

Poster presentations / European Geriatric Medicine 7S1 (2016) S29

S259

S130