European Geriatric Medicine - Supplement 1 - Volume 7 - October 2016

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support and none of them expressed fear from falling. The outcomes in
this population may improve by identification and correction of risk
factors, as well as by advice for use the march support.
P-576
Physical exercise in osteoporotic fracture prevention in older
adults
C. Bento1, J. Caçoilo1, I. Calvinho1. 1Unidade de Saúde Familiar Oriente,
Lisbon, Portugal
Introduction: Osteoporotic fractures are a major health and economic
problem in our rapidly aging society and physical exercise is often
recommended to patients with osteoporosis. Therefore, the purpose of
this systematic review is to investigate the role of physical exercise in
the prevention of osteoporotic fractures in the elderly population.
Methods: Research in PubMed, Cochrane Library and Guideline
databases, using the MESH terms “osteoporotic fracture”, “elderly”
and “physical exercise”, while the search was limited to “systematic
reviews ”, “randomized controlled trials ”, “meta-analysis” and “guide-
lines” of the last “10 years”. The Strength of Recommendation
Taxonomy (SORT) was used in this review.
Results: 12 entries were found, of which 5 guidelines and 3 systematic
reviews, (one was also a meta-analysis) were selected. Entries that did
not evaluate the relation between the variables in study were
excluded. All articles provide evidence (A) that physical exercise
reduces fall risk and improves Bone Mass Density (BMD). Regarding
reduction of fracture risk we can only find low quality and expert
opinion based evidence (C). Most studies are of low quality mainly due
to the fact that osteoporotic fracture is either not an endpoint or is
analysed as an adverse effect and the possible bias towards the
publication of positive results weakens the body of evidence.
Conclusion: There is currently not enough evidence to recommends
physical exercise in osteoporotic fracture prevention as more quality
studies that analyse fracture as a primary endpoint are needed.
However there is Strength of Recommendation A in fall risk reduction
and BMD improvement.
P-577
The influence of a short cognitive and mobility training program
on cognitive functioning among elderly people
E. Bourkel 1, J.-P. Steinmetz1,2, C. Federspiel1,2. 1Centre for Memory and
Mobility, 2ZithaSenior, Research & Development, Luxembourg
Cognitive and mobility training both maintain or improve cognitive
functioning in elderly people. Thus, cognitive and mobility interven-
tions play an important role in the primary and secondary prevention
of dementia. The aim of this study is to further clarify the influence of
diverse training programs on cognitive performances in older adults.
We investigate the effects of cognitive and mobility training on people
with no cognitive disorders and people suffering from mild cognitive
impairments. Furthermore, we determine which cognitive functions
(i.e., memory, cognitive flexibility, fluency and attention) are most
influenced by the training.
The participants (N = 60, age range = 66–87 years) partook in a 12
week mobility and cognitive training program with two sessions per
week. The participant ’s cognitive abilities were assessed before and
after training, using learning and recall memory tests, a cognitive
flexibility test, a verbal fluency test and a nonverbal attention test.
The discussion of the findings focuses on the necessity of introducing
structured cognitive and mobility training programs in the primary
and secondary prevention of dementia in older adults.
P-578
In-hospital mortality among Portuguese octogenarians,
nonagenarians and centenarians
D. Brandão 1–3, A. Freitas1,2, O. Ribeiro2,3, C. Paúl2,3. 1Faculty of Medicine,
University of Porto (FMUP), 2Center for Health Technology and Services
Research (CINTESIS), 3Research and Education Unit on Ageing (UNIFAI-
ICBAS/UP), Porto, Portugal
Introduction: The exponential growth of the oldest old population is
expected to contribute to a higher number of hospital admissions due
to situations of prolonged disability and multimorbidity. Oldest
patients often have complex medical diagnoses and frailty conditions,
which are associated with higher rates of utilization of emergency
services, and a higher risk of experiencing adverse outcomes, such us
mortality. This study aims to analyze trends in-hospital mortality rates
in inpatient hospitalizations byoldest old persons in Portuguese public
hospitals.
Methods: All inpatient episodes of hospital admissions by patients
aged 80 years and older between 2000 and 2014 were considered.
Exploratory descriptive analyses of data regarding in-hospital mortal-
ity were performed.
Results: A total of 1.837,613 episodes of hospital admissions were
analyzed. In 15.6% of the episodes, the patients died. An analysis by
age group revealed that in octogenarians, the percentage of mortality
was 14.3%, increasing in nonagenarians (22.2%) and centenarians
(29.1%). The in-hospital mortality rate decreased from 15.6% in 2000 to
14.6% in 2014. Principal diagnoses at admission with a higher
frequency of in-hospital mortality were pneumonia, acute cerebro-
vascular disease and non-hypertensive congestive heart failure.
Key conclusions: Findings from this study pointed to an increased
vulnerability with age among the oldest old population and that
there is a positive trend in in-hospital mortality. Further studies
should focus on the sociodemographic characteristics of these
inpatients, and on their medium length of stay and presence of
medical comorbidities.
P-579
Fall prediction model in not disabled elderly
D. Cerasuolo, A. Piazzi Tsigler, M. Colpo, G. Sini, P. Palumbo, E. Talluri,
S. Bandinelli. Laboratory of Clinical Epidemiology, InCHIANTI Study
Group, LHTC Local Health Tuscany Center, Florence, Italy; Departement of
Electrical Electronic, Information Engineering University of Bologna
Background and purpose: This study aims to define a predictive
model of the risk of falling in not disabled elderly over a one-year
period using the information obtained from the InCHIANTI Study.
Participants: Participants were selected with the following variables:
Age ≥65, Mini Mental State Examination (MMSE) ≥21, no loss in
Activity of Daily Livings (ADL). Data comes from InCHIANTI Study FU4
and a one-year fall monitoring (Farseeing Project).
Methods: The following parameters were evaluated: Age, Handgrip,
Fall in the previous year, CES-D, Haemoglobin concentration (gr/dL),
Trail Making Test A (TMTA), Level of physical activity (PA), Short
Physical Performance Battery (SPPB), 400 m speed, Fear of falling,
number of drugs. Stepwise selection was performed on a logit
regression model created with the aforementioned parameters using
the AIC criterion.
Results: Forty-two subjects out of 250 (age = 82.1 ± 5.62) reported at
least one fall in the one-year monitoring. Predictivity of the model was
assessed on all subjects resulting with an AUC = 0.74. Internal cross-
validation was performed with a training set equal to 80% of the
subjects and validation set equal to the remaining 20%, resulting with
an AUC = 0.70.
Conclusions: Results suggest that to predict risk of falling in elderly
with good cognitive performance and no loss in ADL the following
parameters are the most influential: Handgrip, Fall in the previous
year, CES-D, PA, Haemoglobin concentration (gr/dL).
P-580
The “3 Plus 1 Integrated Program” improved cardiovascular health
and physical fitness for community-dwelling healthy older adults
in Taiwan
H. Hsu1, S.W. Lin1, C.L. Yang1, L.K. Chen2,3. 1Yangsheng Foundation,
Taipei, Taiwan; 2Aging and Health Research Center, National Yang Ming
University, 3Center for Geriatrics and Gerontology, Taipei Veterans
General Hospital
Poster presentations / European Geriatric Medicine 7S1 (2016) S29–S259 S181