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outcome (CAAP-100% HAAP-67% NAP-100%). When protocol applied,

10 and 30 day-mortality rate were elevated (CAAP 30% and 40%, HAAP

22% and 28%, NAP 66% and 100%).


AP is relevant problem in geriatric population due to the

high mortality rate. Clinical approach is limited due to absence of

stratification for severity. Further studies need to be performed in this

special population in order to optimize medical intervention.


Outcome of geriatric patients with Clostridium difficile associated


J.M. Wendel, S. Langenfeld, M. Vehreschild, R.J. Schulz.

St. Marien-

Hospital Cologne, University Hospital Cologne Germany, Germany


Risk factors of multimorbid patients has to be taken into

consideration in terms of infection diseases like Clostridium difficile,

which is often triggered by careless antibiotic therapies and further

medication with proton pump inhibitors for example. The geriatric

departments take over patients from other clinic departments to

continue started therapies, often antibiotic regiments with all their

side effects and consequences.


In a retrospective case control analyses geriatric patients

with Clostridiumdifficile infectionwere evaluated by the trigger of the

infection and its risk factors. Furthermore various outcome parameters

like kidney function, albumin, potassium and recurrences were analy-

zed. The upcomiong next stepwill be the comparison inmatched pairs.

This is and will be performed as a monocentric clinical trial.


167 patients were identified with Clostridium difficile

infection, 100 evaluated yet. More than 80% were allocated from

other clinical departments. Patients who suffered from Clostridium

difficile associated diarrhea (CDAD) had to stay and to be treated for a

longer period of time. Each individual antibiotic history was

documented and found a high percentage of peniciline, cephalospor-

ine and quinolone therapy as a risk factor for CDAD.


To avoid Clostridiumdifficile associated diarrheawith all

medical, social and economic effects it is most important to rationalize

antibiotic treatment especially by antibiotic stewardship but also to

treat CDAD effectively. Geriatric patients with all their comorbidities

are more vulnerable for CDAD and have a higher mortality. The

amount of recurrences rises.


Zoster Vaccine Live: review of postmarketing safety by decade of


E.D. Willis


, M. Woodward


, E. Brown


, Z. Popmihajlov




Merck & Co.,

Inc., Kenilworth, NJ, USA


Zoster Vaccine Live (ZVL) was approved in 2006 for the

prevention of herpes zoster (HZ) and post herpetic neuralgia in


50 years-of-age. This analysis describes the safety profile

of ZVL by decade of life.


Spontaneous postmarketing adverse event (AE) reports

received for ZVL from 02-May-2006 to 01-Nov-2015 from healthcare

providers (HCP) worldwide for patients age

50 were reviewed.


A total of 11342 reports, containing 28188 AEs, were

identified. The majority of reports were from those 60

69 years

(48%) followed by 70

79 (28%), 50

59 (14%); and

80 years (10%).

Overall, injection site reaction (ISR) (n = 6788; 24%) and herpes

zoster (HZ) (n = 2577; 9%) were the most frequently reported AEs. ISR

was the leading AE in ages 50

79 and HZ in those

80 years. Median

time to onset (TTO) fromvaccination to AE for ISRwas 2 days. In slightly

over half of the reports of HZ, TTO was

14 days postvaccination. HZ

was also themost frequently reported serious AE among all age groups.

In the majority (75%), HZ was considered serious because the HCP

reported the event to be either medically significant or disabling.

Sixteen events (<1%) of disseminated HZ (DHZ) in ages 50

59 (n = 1),


69 (n = 5), 70

79 (n = 6) and

80 years (n = 4) were reported; 40%

of the patients were reported to be immunosuppressed. The remaining

AEs were reported similarly across the age groups.

Key conclusions:

DHZ was reported very rarely. The most frequently

reported AEs for ZVL are similar by decade of life.


Etiology of the bacterial urinary tract infections (UTIs) in elderly


does gender matter?

Z.B. Wojszel


, M. Toczyńska-Silkiewicz




Department of Geriatrics

Medical University of Bialystok,


Department of Geriatrics, Hospital of the

Ministry of the Interior in Bialystok,


Germedica, Specialist Medical

Practice, Bialystok, Poland


Bacterial urinary tract infections (UTIs) are the most

frequently occurring infection in the geriatric population. Often they

require the use of empiric antibiotic therapy, carrying the risk of

increasing bacterial resistance. The aim of the study was the

assessment of gender differences in etiological factors of UTIs in the

geriatric in-patients.


Retrospective analysis of bacteriological urine test results

performed in 2365 patients 60-year-old and older, hospitalized on

non- surgical wards of the Hospital of the Ministry of Interior in

Bialystok (years 2006

2013) was conducted. Patients with bacteriuria

CFU and clinically diagnosed UTIs were selected.


The etiologic factors of 958 UTI cases were identified. Gram-

negative bacteria were found in 87,2% cases of women and in 77,1%

of men (p < 0,001). In women, the most frequently isolated pathogen-

found in 72,2% of cases-was Escherichia coli (versus 40,0% in men).

In men Proteus spp (20,6% versus 6,3% in women),



group (11,8% versus 7,7%), non-fermenting

Gram-negative bacilli (4,7% versus 0,9%), and other Gram-positive

cocci (18,2% versus 9,1%) were more common. Differences in the

frequency of pathogen occurrence between the groups in most cases

were statistically significant.

Key conclusions:

There are significant differences in the profile

of etiological factors of UTIs in geriatric in-patients between men and

women. While the pathogen responsible for the majority of UTIs

among older women is Escherichia coli, the greater share of other

Gram-negative and Gram-positive bacteria in men is observed.

Area: Longevity and prevention


Risk of falls in the elderly: what is our reality?

S. Vieira


, P. Araujo


, S. Amaral


, R. Parreira


, M. Goncalves



C. Damasio




USF do Parque,


USF do Parque,


USF do Parque,


USF do



USF do Parque,


USF do Parque, Lisbon, Portugal


The incidence of falls increases with age and frailty, and

it is estimated to occur in 28

35% of the elderly population (

65 years).

About 10% of falls result in fractures or mortality. In the portuguese

accidents monitoring system, falls in the elderly accounted for 87.1% of

the cases. Our aim is to evaluate the risk of falls in elderly in our

primary care facility.


Timed Up and Go (TUG) and Falls Efficacy Scale (FES) tests

and questionnaires inquiring risk factors, history and consequences of

falls were applied to users

65 years who resorted to consultations at

USF do Parque during a period of thirty days. All data was statistically

processed in Excel.


64 individuals participated in this study, 41 female, with an

average of 79 years. About 45% reported difficulties inwalking and 27%

had at least one episode of fall, resulting in fractures in 2 cases.

However, only 13% used support during the march. No patients

expressed fear to fall through FES but 63% of subjects showed

increased risk for falling through TUG test. These individuals had

risk factors for falling, namely articular/neurological disorders,

benzodiazepines/alcohol consumption.


The proportion of elderly at high risk of fall was high.

Most of the patients did not admit to have difficulty inwalking, fewuse

Poster presentations / European Geriatric Medicine 7S1 (2016) S29