European Geriatric Medicine - Supplement 1 - Volume 7 - October 2016

169 / 290

P-506
Determinants of health related quality of life in elderly
hemodialysis patients
B. Kesikburun, E. Ekşioğlu. Diskapi
Introduction: The aim of this study was to identify clinical and demo-
graphic determinants that can influence health related quality of life in
elderly hemodialysis patients in Turkish population.
Methods: A total of 39 elderly hemodialysis patients participated
in the study. Demographic and clinical data including age, gender,
marital status, education period, duration of hemodialysis, comorbid-
ity, serum level of hemoglobin, albumin, parathyroid hormone, AST,
ALT, calcium, phosphorus, urea, creatinine were recorded. Health
related quality of life measured using Nottingham Health Profile
was investigated. Depression was evaluated using Beck Depression
Inventory. Determinants for quality of life were identified using
multiple logistic regression analysis.
Results: Beck Depression Inventory was significantly associated with
the six domains of Nottingham Health Profile excluding energy
domain (p < 0.05). The factors that significantly affected quality of
life were albumin, hemoglobin, phosphate, creatinine, being married,
number of comorbidities, presence of cardiac disease (p < 0.05).
Conclusion: Depression, some metabolic parameters and number of
comorbidities seemed as the primary determinants of quality of life in
elderly hemodialysis patients.
Keywords: Elderly hemodialysis patient; quality of life; depression.
P-507
Colonoscopy in the old: a geriatric dilemma
M. Krulder1, G.J. Bulte1, F.E.R. Vuik1, J.S.T.S. Droste1, P.L.J. Dautzenberg1.
1Jeroen Bosch Hospital, “s-Hertogenbosch, The Netherlands
Introduction: Colorectal cancer is the third most common cancer in
the Netherlands [1]. Seventy percent of the patients is aged 65 years
or older [2]. The gold standard to diagnose colorectal cancer is
colonoscopy with histology [1].
Methods: Retrospective cohort study of all patients aged 80 years or
older that underwent colonoscopy between January 1st 2014 and
December 31st 2015 at Jeroen Bosch Hospital, a non-academic
teaching hospital.
Results: 465 patients were included with an average age of 82.6 years.
78 patients (16.8%) were diagnosed with colorectal cancer. 70.5%
of the performed colonoscopies had consequences, in 22.2% the
colonoscopy was incomplete, in 4.5% a complication occurred and
13.5% had a bad or reasonable quality of preparation.
Key conclusions: A high incidence of colorectal cancer is found with
colonoscopy, with a low incidence of complications or bad pre-
paration. However, in almost 1 out of 4 patients, the colonoscopy was
incomplete.
References
[1] Landelijke werkgroep Gastro Intestinale Tumoren. Oncoline.
version: 3.0, last
updated 2014–04-16, consulted at 2016-01-21.
[2] Integraal Kankercentrum Nederland. Cijfers over kanker.
Consulted at 2016-01-21.
P-508
Health conditions, life conditions and fragility of elderly patients
hospitalized
M. Lamloum 1, T.B. Salem1, I.B. Ghorbel1, F. Said 1, M. Khanfir1,
H. Houman1. 1University of Tunis El Manar, Tunis, Tunisia
Objectives: increase in life expectancy of the population Tunisian, the
fragility of the elderly has become a major issue in public health for
the coming decades. This phenomenon should be anticipated by
preventive and curative interventions.
Methods: It ’ s through a retrospective study of patients aged 65 years
and over hospitalized in internal medicine between 2004 and 2016,
we propose to describe the living and health conditions in order
to identify vulnerable subjects based on a comprehensive geriatric
assessment and level of fragility with ten criteria, a minimum of three
criteria were used.
Resultats: 120 patients were identified. The average age was 76 years,
the fragility assessment showed that 70% of subjects were fragile.
The fragility factors found are: impairment of higher functions
(depression and/or dementia) (82%), complex treatment (59%), loss
of more than two IADL (58%), female sex (57%) and postural instability
(57%). The analysis of the link between the different clinical criteria
of fragility shows that there is a statistically significant relationship
between the age of more than 75, female gender, impairment of
mental ability and loss of autonomy. There is a statistically significant
relationship between the get up test and the pathological go (there is a
risk of falling) ant postural instability: 63% of the unstable had a
pathological test while only 9% of the stable had had it.
Conclusion: A better understanding of the health and living con-
ditions of the elderly can identify those who are most vulnerable
among them.
P-509
Do elderly breast cancer patients with primary endocrine
treatment receive second line treatment?
M. Landman1, J. Verloop2, H. Maas1. 1Twee Steden ziekenhuis, Tilburg,
2IKNL, The Netherlands
Objectives: Primary endocrine therapy (PET) for non-metastatic
breast is increasingly prescribed in elderly women in the
Netherlands (up to 28% in 2008). Nevertheless tumor progression is
observed in a substantial portion of PET-treated patients. The aim of
our population-based study was to evaluate prescription of PET in
more recent years (2009– 2014) and to describe the use of second-line
therapy.
Methods: Patients above 74 years, diagnosed with breast cancer (T1-
4NxM0) between 2009 and 2014, were selected from the Dutch
National Cancer Registry. Data were extracted on hormonal status,
prescription of PET, second-line therapies (initiated 6 months after
starting PET) and vital status up to 1-2-2015. In a regional subset of the
Registry comorbidities at time of diagnosis were recorded.
Results: Use of PET increased during the study-period (27% to 32%).
4,111 patients with T1-3NxM0 (31% had stage 1, 65% and 4% respec-
tively stage 2 and 3) and 736 patients with T4NxM0 breast cancer
received PET. 96% of the tumors were estrogen positive. Respectively,
64% and 51% of patients with T1-3 and T4 cancer had ≥2 comorbidities.
In T1-3 tumors 6% had surgery as second-line treatment, while 2%
received radiotherapy; In T4 stage 8% received surgery and 5%
radiotherapy. 0% received chemotherapy. Within median follow up
of 20.3 months, 43% of women with T1-3 tumors and 49% with T4
tumors had died.
Conclusion: Use of PET in elderly women aged with non-metastatic
breast cancer still increases over time. Only a small minority receives
second-line therapies after starting PET. Both, relatively high short-
term mortality and the incidence of multimorbidity suggest PET is a
valuable treatment option in these patients.
P-510
A propose of a geriatric case: dural arterio-venous fistula (DAVF)
left in a 81-years-old, geriatric patient
W. Lopez1, A. Rodriguez1, L. Cueto2, E. Zafra1. 1Hospital virgen of Valle,
2Hospital virgen of salud, Toledo, Spain
Introduction: Intracranial dural arteriovenous fistulas (DAVFs) are
acquired lesions characterized by the focal area of abnormal arterio-
venous fistulous connections with in the dura. The main symptoms
are pulsatile tinnitus, ocular pain, diplopia and exophthalmia. and
Intracranial DAVFs can culminate in acute intracranial hypertension
and focal neurological signs due to intracranial hemorrhage. In this
report, one related unusual clinical case which was resolved in our
department, is presented, followed by a review.
Poster presentations / European Geriatric Medicine 7S1 (2016) S29–S259 S163