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The majority of patients were women (86/83,5%), and both

age groups were represented at similar rates (49/47,6% at age 60


The mean age at the moment of AAI implantation was 74,9 ± 5,7 years.

The mean observation time was 62,1 ± 23,3 months. Both mortality

and frequency of paroxysmal atrial fibrillation were similar in both

groups, while AAI had to be replaced with DDD significantly more

frequently in the younger age group. However, the prevalence of severe

defects of atrioventricular conduction was low in both age groups.

The mean time to the replacement was 5,6 ± 1,9 years.


AAI stimulation in patients 75+-year-old seems to be as

safe as in the young-old.


Outcomes in an orthogeriatrics Portuguese unit

N. Gómez


, D. Silva


, M. Ardérius


, A. Jordão




Internal Medicine

Department- Sector III, Hospital Pulido Valente- North Lisbon Hospital

Center, Lisbon, Portugal


Pernicious anemia accounts for 80% of case of mega-

loblastic anemia. It is an autoimmune disorder with an insidious

clinical course and highly variable clinical spectrum, including

constitutional, neurological, hematological and gastrointestinal

symptoms. A systematic approach is essential for the establish-

ment of a definitive diagnosis and institution of an appropriate

treatment plan.

Case Report:

A 76 year-old woman living in Portugal, with a personal

history of asthma and chronic venous insufficiency, under no chronic

medication and having regular nutritional habits, who was admitted

for investigation of a clinical picture of asthenia, anorexia, 6% of body

weight, symmetric lower limb paresthesias and cognitive impairment

with 6 months of evolution. At physical examination normal cognitive

function and pallor of the skin and mucous membranes. Laboratory

tests showed pancytopenia (WBC) of 2.10 × 10


/L, with macrocytic

anemia (Hgb) 7.1 g/dL and platelets 71.000 × 10


/L. Evidence of

hemolysis on peripheral blood smear, haptoglobin <8 mg/dL and

lactate dehydrogenase 1,528 U/L. Significantly, vitamin B12 was low

<108 pg/mL, and testing for parietal cell, and intrinsic factor anti-

bodies resulted positive, confirming the diagnosis of pernicious

anemia. For further investigation she underwent an upper gastro-

intestinal endoscopy, which described atrophic gastritis of the body of

the stomach, The patient began intramuscular cyanocobalamin

replacement therapy, with clinical stability and reversion of symptoms

and hematologic disturbances


The diagnosis of anemia in the elderly is important to

investigate and treat the underlying cause. Aging, by itself, is not a

cause of anemia. When pancytopenia exists as initial presentation, the

etiologic diagnosis is complex. Early testing should be encouraged as

the treatment is simple and procures a good prognosis.


anemia; pernicious; megaloblastic; pancytopenia;

vitamin B12; elderly.


Cancer in elderly patients: anatomo-clinical aspects and

therapeutic strategy

S. Aloulou


, S. Hammami


, W. Amorri


, A. Benhmida




Gabes Hospital,


CHU F Bourguiba, Faculty of Medicine, Monastir, Tunisia


In Tunisia, we arewitnessing an increase in life expectancy

but also an incidence of cancer in the elderly population. We aim to

identify the anatomoclinical features of elderly suffering cancer in

southern Tunisia, describe the main geriatric assessment tools and

reporting published data on the general principles of the elderly care



This is a prospective study focusing on a case study of 65

elderly suffering from cancer in the Medical Oncology Service of the

Regional Hospital of Gabes between January the 1st 2013 and October

31, 2013. All patients had evidence of cancer and input data were

proved by the SPSS 18.0 software.


The average age of patients was equivalent to 75 years and 6

months (ranging from 65 to 93 years). The median was equal to 75

years. Our study consisted of 39 men and 26 women. Most of the

patients were from Gabes governorate (52%). 77% were retired people.

72% had an average financial level. The financial resources were

mainly a monthly pension for 49 patients (75%). 85% were insured

by CNAM. 50.8% were smokers, 18.5% were occasional alcoholics.

50.8% had high blood pressure, 30.8% were diabetes and 10.8% were

suffering cardiac disease. The most common types of cancer were

colorectal cancer (21.5%) and lung cancer (24.6%). In the bronchial

cancer group was the predominant epidermoid carcinoma (12 cases).

The length of consultation period ranged from 1 to 12 months (the

average of 4.5 months). The majority had a locally advanced tumor or

metastatic cancer. The tumor was classified as T3 for 38% and T4 for

49% of cases. The tumor was associated with lymph node damage in

59% of cases. 47% had metastases at the time of diagnosis and thus

classified M1. Our patients were classified according to geriatric

evaluation scale defined by Balducci with 3 classes: Autonomous

without frailty criteria (37 patients), vulnerable (20 patients) and

critical (8 patients). 29 patients (44.6%) made surgery on early-stage

cancer. 49 patients (75.4%) had received chemotherapy for palliative

stage IV disease in 49% of cases, healing in 51% of cases. 15.4% had had

x-ray therapy. Only one patient had received in adjuvant Herceptin.

The average survival time was 11 months (ranging from 3 to 22



A close collaboration between oncologists and geriatri-

cians is needed in order to properly assess the elderly and to optimize

the therapeutic strategy. The inclusion of elderly in clinical testing is



Is malnutrition a cardiovascular risk factor for heart rhythm

disorders in elderly?

A.I. Pâslaru


, A.C. Ilie


, I.M. Crăcană


, N. Lefter


, G.I. Prada


, I.D. Alexa




Department of Internal Medicine, University of Medicine and Pharmacy

Grigore T. Popa



Dr. C.I. Parhon

Hospital, Iaşi,


Department of Geriatry

and Gerontology, University of Medicine and Pharmacy

Carol Davila


Bucuresti, Romania


Normal ageing is associated with a higher incidence of

cardiac arrhythmias due to multiple factors: physiological changes in

cardiovascular system, the constant increase of cardiovascular risk

factors. Malnutrition is an


but independent cardiovas-

cular risk factor for senior population, but with few data regarding the

relationship with arrhythmias.


We present a prospective, observational study on 481

patients over 65 years of age, which were divided into two groups:

with and without arrhythmias. They all underwent a geriatric

evaluation including Mini Nutritional Assessment (MNA) and

other geriatric evaluation scales. We measured serum levels of



risk factors; also all patiens had an ECG and



66.32% patients had arrhythmias, with no significant

differences regarding gender, body mass index, smoking status.

Arrhythmias were significantly higher in patients over 75 years

(p = 0.034). There was no difference between groups regarding some


cardiovascular risk factors and



factors such as ventricular mass, and nutritional status. The arrhyth-

mia group had a higher level of cholesterol (p = 0.005), triglycerides

(p = 0.015), uric acid (p = 0.018) and also a significant difference

regarding inflammatory status (p = 0.017). There were no differences

regarding studied geriatric syndromes between groups.


The influence of traditional and nontraditional risk

factors is not the same in arrhythmias as part of cardiovas-

cular diseases. Some of them have a constant negative influence

but there are factors such as malnutrition, depression, LDL-C, and

HDL-C levels that have a smaller impact on arrhythmias in senior


Poster presentations / European Geriatric Medicine 7S1 (2016) S29