European Geriatric Medicine - Supplement 1 - Volume 7 - October 2016

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the following patterns were found: cardio-respiratory (CAD, HF,
arrhythmias, respiratory diseases), metabolic, renal, mental (CI only),
and mental-neoplasm (depression and neoplasm).
Conclusion: Prevalence and importance of the particular multi-
morbidity patterns differ and depend on age that should imply
further research on implementation of the individual, patient-
centered secondary and tertiary prevention and treatment strategies.
P-210
Patterns of sleep in older people with mood disorders
G.I. Prada1,2, R.M. Nacu1,2, L.E. Lungu1,2, G. Cerchez2, A.G. Prada2,
A.C. Ilie 3, A.I. Pislaru3, I.D. Alexa3, A.M. Herghelegiu1. 1“Ana Aslan”
National Institute of Gerontology and Geriatrics, 2“Carol Davila”
University of Medicine and Pharmacy, 3“Gr.T. Popa” University of Medicine
and Pharmacy, Iasi, Romania
Introduction: Both sleep and mood disorders are often encountered
in elderly, have impact on quality of life and morbidity, and influence
each other. Aim of the study was to compare sleep disorders in elderly
and adults diagnosed with mood disorders.
Material and method: We analyzed 2 randomly selected groups of
adults and older patients, total of 240 subjects, 60 men and 60 women
in each group. A previously validated questionnaire has been used to
assess sleep, with a total of 23 items. Neuropsychologist evaluated
mood disorders. 73% adults and 90% elderly resided in urban area.
Over 35% adults had higher education and 60% elderly had medium
education.
Results: Significantly more elderly (18%) as compared to adults (5%)
lost their spouse. 1/3 of subjects in both groups felt tired after waking-
up; 84% adults and 60% elderly continued to feel tired whole day.
Adults had significantly more often (p < 0.001) altered sleep program.
2/3 of elderly had difficulty with initiating sleep. Most elderly slept 4
hours daily, statistically significant difference from adults (p < 0.01).
Elderly woke-up during night because of various pains and renal
conditions, while adults because of depression. Women had sleep
disorders mainly due to depression in both age-groups. Nightmares
were more prevalent in elderly (p < 0.05). Elderly with mood disorders
sleep less (p < 0.01), wake-up during night. Elderly describe more
often poor quality of sleep (p < 0.01).
Conclusions Sleep disorders are more prevalent in women. Elderly
with depression sleep less, wake-up more often during night and take
longer to sleep again than adults.
P-211
Non-pulmonary symptoms and comorbidities in older peoplewith
chronic obstructive pulmonary disease
G.I. Prada1,2, M. Markovits2, R.M. Nacu1,2, L.E. Lungu1,2, A.G. Prada2,
A.C. Ilie 3, A.I. Pislaru3, I.D. Alexa3, A.M. Herghelegiu1. 1“Ana Aslan”
National Institute of Gerontology and Geriatrics, 2“Carol Davila”
University of Medicine and Pharmacy, Bucharest, 3“Gr.T. Popa” University
of Medicine and Pharmacy, Iasi, Romania
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is
frequently seen in elderly, with important consequences on morbidity
and mortality. We analyzed non-pulmonary symptoms and comorbid-
ities in elderly with COPD.
Material and methods: A retrospective study performed on 120
randomly selected patients previously diagnosed with COPD, divided
into 2 equal groups: adults (50 –64 years), elderly (≥75 years), with
equal number of women and men.
Results: Almost all subjects had no occupational risk. 2/3 of patients
resided in urban area; 77.5% were current or previous smokers, mainly
males (58%). 16.7% had tachycardia and 2.5% had bradycardia, more
often encountered in elderly. Heart failure was more prevalent in
elderly (p < 0.05), 1 in 7 having ejection fraction ≤40%. Pulmonary
hypertension was more prevalent in adult women chi-square test =
4.261 (p < 0.05). C-reactive protein more prevalent in elderly (p <
0.01). Body Mass Index higher in adults, chi-square test showed no
gender difference. High prevalence of diabetes mellitus amongst
elderly, no significant difference from adults. Pearson test showed no
statistical correlation between COPD severity (GOLD category)
and HbA1C levels. Osteoporosis more prevalent in elderly women
(chi square = 10.652, p < 0.05). Regarding neurocognitive status, only
decreased orientation skills in elderly group and anxiety in women in
both age-groups. Comorbidities were highly prevalent in both groups
(92%), elderly having more than 3 conditions concomitantly. Most
prevalent comorbidities in elderly, in order: diabetes mellitus, heart
failure, hypertension.
Conclusions: Comorbidities and non-pulmonary symptoms in elderly
with COPD have a significant impact on severity of disease and survival
in this category of patients and need special attention.
P-212
High Red Cell Distribution Width is able to predict hospitalization
for heart failure in elderly patients with coronary artery disease
A. Pratesi1, F. Orso1, A. Baroncini1, E. Carrassi2, C. Ghiara2, S. Parlapiano2,
A. Herbst2, N. Marchionni1, M. Di Bari 1, S. Baldasseroni1. 1Department of
Experimental and Clinical Medicine, Careggi University Hospital,
University of Florence, 2University of Florence, Florence
Introduction: Red Cell DistributionWidth (RDW) is found to be a very
strong independent predictor of morbidity and mortality in patients
with chronic heart failure. We aimed to analyse whether RDW was
a predictor of hospitalization for heart failure in patients with
Coronary Artery Disease (CAD), with or without left ventricular
systolic dysfunction (LVSD).
Methods: We prospectively enrolled patients with stable CAD with or
without LVSD from our Outpatient Clinic from 2009 to 2013. Each
patient underwent clinical and biohumoral evaluation; a telephone
follow-up was planned to register long-term outcomes. Sensitivity/
specificity ratio for RDW was analysed with ROC analysis and the
independent role of RDWwas evaluated with Cox regression model of
analysis.
Results: 152 patients were enrolled with mean age 69.1 ± 10.8; the
mean left ventricular systolic function was 43.9 ± 14.9%. Mean time
followupwas 1,340.9 ± 803.7 days, mortality ratewas 20.9% (32 deaths)
and hospitalization for heart failure rate was 27.5% (42 events). Mean
value of RDWwas 14.8 ± 3.0%; the analysis of the ROC curve identified a
RDW cut-off level of 13.2% (AUC 0.781; p < 0.0001). Patients with
RDW> 13.2% had significant independent (adjusted for age, sex, NYHA
class, NT-proBNP, Ejection Fraction and eGFR) higher risk of hospital-
ization for heart failure (HR = 6.50; 95% CI: 2.40–17.70). Its predictivity
remained significant either in patients with LVSD and in thosewithout.
Key conclusions: In patients with CAD with or without LVSD, RDW
value of >13.2% independently predicts increased risk of hospitaliza-
tion for heart failure.
P-213
Characterization of comorbidities in a geriatric inpatient
population
J.O. Ribeiro1, J.P. Machado1, S.C. Martins1, A.A. Nunes1, J. Marques1,
E. Oliveira1, J. Alexandre1, A. Monteiro 1. 1Centro Hospitalar Tondela-
Viseu, Viseu, Portugal
Introduction: With the ageing of population, a great percentage of the
patients on the daily practice of Internal Medicine are elder. This
population is associated to a significant number of comorbidities. This
work results from the challenge to characterize the geriatric inpatient
population of one Internal Medicine ward.
Methods: In order to characterize the population, the clinical
codification sheets of 200 patients in a ward of Internal Medicine
during the year of 2015 were requested, the patients aged 85 years old
or over were selected, and the data was evaluated.
Results: Of the total, 69 patients (34,5%) are aged 85 or older. The
average age is 90,0 years old. There were 38 (55.1%) female patients
and 31 (44.9%) males. A number of 15 patients came from nursing
homes, 17 were confined to bed, 5 had pressure ulcers and 21 were
demented. Concerning the comorbidities, 22 (11%) were diabetic, 48
Poster presentations / European Geriatric Medicine 7S1 (2016) S29–S259 S84