European Geriatric Medicine - Supplement 1 - Volume 7 - October 2016

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Aim: Parkinson ’ s disease (PD) showa more favorable cardio-metabolic
profile respect to general populations. Moreover, scanty evidence
suggests that the likelihood of suffering from hypertension decreases
during the PD course. We evaluated the association of PD duration
with diagnosis of hypertension, assessed by office measurements and
24-hour (ambulatory) monitoring, as well as the agreement between
these two methods.
Methods: We evaluated 167 PD patients, consecutively admitted to a
geriatric Day-Hospital. All participants underwent a comprehensive
clinical evaluation. Hypertension was evaluated through both office
and ambulatory blood pressure measurements, according to the
European Society of Cardiology recommendations.
Results: Among participants (mean age 73.4 ± 7.6 years; 35% females),
the prevalence of hypertension was 60% and 69% according to office
and ambulatory blood pressure measurements, respectively (Cohen ’ s
k = 0.61; p = <0.001). After adjusting for potential confounders, PD
duration was inversely associated with hypertension as diagnosed by
office measurements (Odds Ratio [OR] 0.92; Confidence Interval [C.I.]
95% 0.86 –0.98), but not by ambulatory monitoring (OR 0.94; C.I. 95%
0.81–1.01). Analysis of the ambulatory blood pressure pattern showed
higher nocturnal blood pressure among patients with longer disease
duration.
Conclusion: Ambulatory blood pressure monitoring improves the
detection of hypertension by 15% in PD, respect to office evaluation.
The likelihood of suffering from hypertension does not decrease
during the PD course; rather, blood pressure pattern seems to shift
towards nocturnal hypertension. Relying on office measurements
might lead to underestimation and under-treatment of hypertension
in PD, especially in late disease stages. Ambulatory blood pressure
monitoring should be routinely performed in these patients.
P-165
High prevalence of iron deficiency in a Dutch geriatric migrant
population
C.L. Brederveld 1, J.P. van Campen1, N. Van der Velde2. 1MC Slotervaart,
2AMC, Amsterdam, the Netherlands
Objectives: Prevalence of iron deficiency anaemia rises with age [1].
Potentially migrants are at higher risk for IDA because of differences in
intake and uptake as well as higher comorbid status [2]. Independently
of the underlying disease, iron deficiency anaemia (IDA) leads to an
increase in mortality thus warranting further diagnostics and
treatment [3]. We assessed whether geriatric Turkish and Moroccan
migrants have a higher prevalence of low iron status and IDA.
Methods: Retrospective case-control study in a geriatric outpatient
clinic (2012 –2015). In total, 188 consecutive Turkish and Moroccan
migrants 65 years and older were included and matched with 188
Dutch controls. Main outcome measures were serum ferritin level
(below 15 μg/L) and IDA. Multivariate logistic regression was perfor-
med to correct for confounders.
Results: Mean serum ferritin level was significantly lower in migrants
(83.46 μg/L, SD = 106.8 vs. 164.94 μg/L, SD = 160.1, (p < 0.05)). In total,
7.4% met IDA criteria, of these 5.6% were migrants and 1.8% was Dutch
(p < 0.05). After correction for age, gender, BMI, and use of NSAID ’s,
iron deficiency remained associated with migrant status (OR 3.0, 95%
CI 1.0–8.9) as was IDA (OR 2.9, 95% CI 1.2–7.2).
Conclusion: Prevalence of iron deficiency and IDAwas increased in the
first generation Turkish and Moroccan geriatric migrant population.
This might be caused by differences in iron intake or uptake from
nutrition between the populations or because of gastrointestinal
pathology, further study is warranted.
References
1. Choi C.W. et al. The cutoff value of serum ferritin for the diagnosis of
iron deficiency in community-residing older persons. Ann. Hematol.
84, 358–61 (2005).
2. Schellingerhout R. Gezondheid en welzijn van allochtone ouderen.
Sociaal Cultureel Planbureau (2004).
3. Goddard A.F., James M.W., McIntyre A.S., Scott B.B. Guidelines for
the management of iron deficiency anaemia. Gut 60, 1309– 16
(2011).
P-166
Identifying loneliness in the elderly population during inpatient
stay
A. Chauhan1, M. Watanabe1, R. Li1, N. Cotton1, S. Thompson2. 1Hertford
College, University of Oxford, 2Geratology Department, John Radcliffe
Hospital, Oxford University Hospitals
Objectives: Loneliness, the perception of social isolation, is increas-
ingly considered a major healthcare concern for ageing populations. A
growing body of evidence identifies correlations between subjective
and objective measures of social isolation and a higher incidence of
early mortality, and cognitive and functional decline. Understanding
the prevalence of loneliness and its associations would enable further
characterisation of this link. This study investigated the prevalence
of loneliness amongst the elderly inpatient population, in whom its
relationship with adverse outcomes could have a significant impact.
Methods: 50 consenting, non-confused inpatients older than 75 years
on acute general medical wards were interviewed. A questionnairewas
used to measure subjective patient-reported loneliness and objective
measures of social isolation both before and during patient admission
(living alone pre-admission, visitor frequency whilst inpatient).
Furthermore, we asked whether the participants would welcome
increased social contact as a social intervention.
Results: Our results show that 36% of participants experienced some
subjective loneliness during their admission, and 10% experienced
significant loneliness. There were no significant correlations with age,
gender, or admission duration at the time of questioning. Perceived
loneliness could not be reliably identified by objective measures of
social isolation before or during admission, or by subjective loneliness
pre-admission.
Conclusions: Therefore, loneliness is a common experience in the
elderly inpatient population, which objective measures of social
isolation may not reliably reveal. In this context, patient-measured
loneliness questionnaires should be used to screen those at risk, in
order to better identify these patients for future research and
appropriate intervention.
P-167
Prevalence of frailty in end-stage renal disease patients under
dialysis and its association with clinical and biochemical markers
V. Poveda1,2,3, M. Filgueiras 4, V. Miranda4,5, A. Santos-Silva6, C. Paúl1,3,
E. Costa6. 1Abel Salazar Biomedical Sciences Institute, University of Porto,
Porto, Portugal; 2University of Santa Elena, La Libertad, Ecuador;
3CINTESIS – Center for Health Technology and Services Research,
University of Porto, Porto, 4Hemodialysis Clinics of Gondomar, Gondomar,
5Hemodialysis Clinics of Felgueiras, Felgueiras, 6Department of Biological
Sciences, UCIBIO, Faculty of Pharmacy, University of Porto, Porto, Portugal
Objectives: Considering the lack of information about frailty in end-
stage renal disease (ESRD) patients under dialysis, the aims of this
work was to evaluate the prevalence of frailty in these patients, and
its association with socio-demographic, clinical and biochemical
markers.
Methods: We performed a cross-sectional study with 83 ESRD
patients (44 males and 39 females, 64.3 [±14.6] years old) on regular
dialysis. The classification of the ESRD patients as robust, pre-frail and
frail was performed using the FRAIL questionnaire. Moreover, it was
also evaluated the social support, as well as data about socio-
demographic and comorbidities, and haematological, iron status,
dialysis adequacy, nutritional and inflammatory markers.
Results: Our group of ESRD patients showed a prevalence of pre-frailty
and frailty of 54.2% and 28.9%, respectively. When compared the 3
groups of patients, we found a significant increase in proportion of
female, diabetes and hypertension in frail group. A significant increase
in ferritin level, global deterioration scale score, Beck depression
Poster presentations / European Geriatric Medicine 7S1 (2016) S29–S259 S72