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We analyzed 166 patients out of 196 included (mean age

80.5 ± 7.8 y, women (W) 81.8 ± 7.1, men (M) 77.8 ± 8.6 y, p = 0.0018). 30

patients were excluded for medical reasons, e.g. delirium. AF in W/M

were 2.8 ± 0.72/3.16 ± 0.65, p = 0.0019), while serum levels show no

sex difference (CML W 365 ± 134, M 372 ± 133, A/P W 464 ± 123, M

489 ± 126 ug/mL; 330/405 nmW 2.21 ± 0.98, M 2.35 ± 1.13, 440/

520 nmW 9.44 ± 5.75, M 9.68 ± 5.9, 280/350 nmW 34.5 ± 5.6, M

34.6 ± 5.8, 360/440 nmW 3.14 ± 0.95, M 3.26 ± 0.98 mg/mL, all n.s.).

Mean BI at admissionwas 50.4 ± 18.9 inWand 47.3 ± 20.9 in M (n.s.), at

discharge W 73.8 ± 21, M 77.8 ± 20.8 (n.s.). No significant correlation

was found except for A/P inM for BI at discharge (r =

0.2909, p = 0.05).

Mean MMSE was 23.1 ± 4.8 (W 22.9 ± 4.8, M 23.3 ± 4.9, n.s.) and show

no correlation to AGEs, but MMSE subscore immediate recall do to CML


0.1666) and 280/350 nm (r 0.2035, p = 0.05 each). MMSE subscores

in M were n.s., while in W CML (r

0.209) and 280/350 nm (r 0.2464)

for immediate and A/P (r 0.1977) for delayed recall showed significant

correlations (p = 0.05 each).


Sex differences in AGE skin measurements were not

confirmed by serum analysis. We found no correlation between AGEs

and functional outcome and no sustained correlation between AGEs

and cognition in our cohort. Inwomen different MMSE subscores show

some significant correlation wor different subclasses of AGEs.


Macrocytic anemia in elderly

Dorra Nessib, Said Fatma, Ben Salem Thouraya, Imed Ben Ghorbel,

Khanfir Monia, Mounir Lamloum, Houman Mohamed Habib.




The prevalence of anemia rises with advancing age.

In effect, macrocyticanemia is a common condition in the older popu-

lation and may receive adequate attention in clinical practice because

of its impact on quality of life.


It is a retrospectivestudy of medical records of patients

hospitalized between 2003 and 2016 who were 65 years of age or over

and who had a macrocytosis.


Twenty-three patients were recorded (14 men and 9 women)

with the aver age of 75 years. Functional signs were poor general

state in 9 cases, asthenia in 17 cases and digestive complaints in 5

cases. The clinical examination showed lymphadenopathy in 1 case

and vitiligo in 1 case. One patient had isolated macrocytosis without

anemia. The hemoglobin level was between 4 and 10 Leucopenia

was reported in 10 cases and thrombocytopeniain 7 cases. Hyperho-

mocysteinemia was seen in 4 cases. Eight patients had Biermer


disease (megaloblastosis, atrophic gastritis and low serum cobalamin

level). Nine patients had a cobalamindeficiency (not associated to


s disease). 3 patients had myelodysplasic syndrom, 1 patient

had mantlecelllymphomain, 1patient had a multiple myeloma.

Complementary investigations which helped the most in etiologic

diagnosis were bone narrow examination and fibreopticendoscop.


Macrocytic anemiamay be often un recognized because of

its subtle clinical manifestations. Although vitamin deficiency is the

mostf requent etiology, it is important in patients presenting only with

macrocytic anemia to search for early signs of malignant neoplasms.



s syndrome in elderly patients

B.S. Thouraya, Z. Meddeb, M. Sabrine, B.G. Imed, L. Mounir, H.M. Habib.

Internal Medecine



s syndrome (SS) is a systemic disease affects

femaleswaround 50 years. The aim of thisstudywere to compare the

clinical, biologicalfeatures ofelderly SS compared to younger. Material

Retrospectivestudycompiled SS patients.Thediagnosiswasbased on

the American

European Consensus Group classificationcriteria for

SS.Patients weredividedintotwo groups(G1: age >65years; G 2: age

<65 years). Clinical, biologicalcharacteristics of the 2 groups were-

comparedusing the X2 and Fisher test.


118 patients wereincluded: 14 in G1and 104 in G2. The

meanage at diagnosiswas 69 G1 and 46 years G2. 93% hadxerostomia,

100% hadxerophthalmia, 36% hadsuperficialkeratitis, parotidhyper-

trophywasnotedin 14%. Arthralgiawerereported by 71.4% andarthriti-

sin 7%. One patient hadlungdisease one hadvascular purpura and one

hada central nervousdisease. Peripheralneuropathywasobjectifiedin

3 cases. 46% of patients hadlymphopenia, 23% hadanemia, 61.5%

hadhypergammaglobulinemia and 38.5% had an inflammatory syn-

drome. Antinuclearantibodies (ANA), autoantibodiesagainst SSA and

SSBwere positive in 63.6%, 40% and 20%. The comparisonwithyounger

patients showed no significantdifference in differentclinical and

biological manifestations. antimalarialdrugs and corticosteroidswer-

eused more frequently inG1.


Diagnosis of SS in elderlycanbedifficultgiven, because-

medicationsmayberesponsible for a dry syndrome and the frequency

of ANAwithoutpathologicalsignificance. visceral manifestations and

positivity of autoantibodiesfacilate the diagnosis.


Liver abscess of odontogenic origin, in a patient with dental

implantation procedure history

K. López-López, E.L. López-López, C.E. López-López, R.B. Tineo,

M.S. Antón, V.J. Hernández.

Hospital San Juan de Dios, Burgos, Spain


Pyogenic liver abscess, a potentially life-threatening

disease. It may be caused by biliary tract pathology, colonic disease,

hematogenous seeding, recent gastric or enteric surgery, direct trauma

or pancreatitis, or may be of cryptogenic origin. Dental disease as a

source of hepatic abscess is extremely rare, especially in immuno-

competent patients. We report a case of liver abscess of odontogenic

Case Report. We report an immunocompetent 75-year-old male

with undergoing dental implantation procedure 2 months before

hospital admission; Independent daily living activities, non-cognitive

impairment, live with his sister. Clinical history: hepatic disease

(primary biliary cirrhosis), diabetic. Medication was taken: glargine

insulin 10 units at day. He starts with a 1-week history of fever, chills

and headache. He had previously been healthy, Three weeks before

hospital admission; He was admitted at intensive care unit, was

performed drainage of liver abscess one blood culture grew Prevotella

oris , bacteria that are commonly found inside the oral cavity. Bacterial

culture of the liver abscess drainage sample grew both Prevotella and

streptococcus constellatus. This led to our diagnosis of pyogenic liver

abscess of dental origin, after antibiotic therapy with drainage,

abdominal sonography showed resolution of the abscess. Patient was

performed geriatric assessment and start recovery in the geriatric

ward after 45 days, the patient was complete recover.


Pyogenic liver abscess is a relatively uncommon but

important disease, which can be fatal Therapy for pyogenic liver

abscess usually requires percutaneous drainage combined with

intravenous administration of antibiotics. Antibiotic prophylaxis may

prevent hepatic abscess in patient with liver disease


Has patient

s with hip fracture profile changed?

E. Martín De Francisco


, B. Alvira Rasal


, E. Garcia Gomez


, A. Malanga



, J. García Fernandez




Hospital Infanta Elena,


Hospital Sanitas

La Moraleja


We aim to evaluate the evolutionary changing charac-

teristics of patients admitted to our Orthogeriatric Unit over the last

five years.


Retrospective descriptive study of patients over 65 years

old admitted for hip fracture to Hospital Infanta Elena Valdemoro

(Madrid). We collected twenty five sociodemographic, functional and

cognitive status concerning variables and analyzed them with SPSS



The sample consists of a total of 138 patients corresponding

to 73 incomes taken place from June to December 2015 and 65

income from June to December 2010. In the first group the mean age

Poster presentations / European Geriatric Medicine 7S1 (2016) S29